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It is important for those who are pregnant or lactating to ensure they get enough B12 from their diet or supplements to avoid becoming deficient or passing a deficiency to their baby

4.4 Long-term safety and off-target effects Emerging reports link GLP-1RAs to rare ocular adverse events, including NAION ( 5 Conclusion In conclusion, the expanding body of evidence supports that GLP-1RAs offer a multifaceted approach to ocular therapeutics by targeting key molecular pathways involved in retinal neuroprotection, mitochondrial regulation, inflammation, vascular remodeling, and angiogenesis

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Treated animals show increased oxygen consumption and energy expenditure measured by indirect calorimetry, confirming enhanced metabolic rate

Effects on the motility of intact spermatozoa and on sperm axonemes